AC Immune SA entered a research partnership with leading scientists in the Perelman School of Medicine at the University of Pennsylvania (Penn) focused on studying the pathological mechanisms of TDP-43 misfolding and aggregation.   TDP-43 is a recently identified target of growing interest for neuro-orphan indications such as frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). It also plays an important role in other significant neurodegenerative indications such ...